MastersinDataScience.org is owned by 2U, LLC, parent company of edX. Our goal is to help learners make confident, informed decisions about their education and career. Some programs shown here are offered by universities that partner with 2U, for which 2U provides marketing and operational support and receives compensation. Other programs shown may be paid advertisements from third parties. Both types of programs are identified with the word AD or Advertisement. We aim to keep information current and accurate. Learn more about edX and our partners.
Online Master’s Degrees in Information Systems
An information system (IS) integrates hardware, software, and people to collect, process, store, and distribute information within an organization. They play a crucial role in how businesses conduct day-to-day operations and plan long-term strategy.
A Master of Science in Information Systems (MSIS) can equip you with the skills to start or advance your IT career. Some technical positions that frequently require knowledge of information systems include:
- Systems Analyst
- Information Architect
- Database Administrator
Interested in management roles? Earning your MSIS may better position you for advancement to obtain a mid- or senior-level title, such as:
- Chief Information Office
- Project Manager
- Webmaster
The programs featured on this page were last updated in April 2026. For the most current program information, please refer to the official website of the respective school.
What Is an Online Master’s Degree in Information Systems?
An online master’s degree in information systems is a graduate program focused on how organizations use technology, data, and business processes to support operations and decision-making. Depending on the school, these programs may be titled Master of Science in Information Systems (MSIS) or use related names such as information systems technology or computer information systems.
Many programs combine technical coursework with business-oriented study, but the balance varies by institution. Some emphasize IT management, project leadership, cybersecurity, analytics, or enterprise systems, while others focus more on systems development, databases, or applied technical problem-solving.
If you’re considering an MSIS to start or advance your career, compare programs closely to see whether their curriculum, delivery format, and specialization options match your goals.
Online Master’s in Information Systems Course Examples and Admission Requirements
While a master’s degree in computer science can prepare you to design and develop information systems, an MSIS can give you the knowledge to apply those systems within a business context.
MSIS programs can cover a broad range of topics related to how organizations use technology, data, and business processes.
- Business and technology foundations
- Specialized topics such as cybersecurity, data analytics, artificial intelligence, or business intelligence
- Technical tools and methods, such as database management systems, programming, and systems analysis
- Management, project leadership, and decision-making skills
- Ethical, legal, and governance considerations
- Emerging technologies and their business applications
Depending on the program, students may also complete applied learning experiences such as internships, capstone projects, consulting projects, or practicums.
Before applying to MSIS programs, make sure you understand and meet each program's requirements. You may need to provide proof of your work experience or demonstrate your leadership skills. Technical programs may ask you to prepare prior coursework or prove your knowledge around topics related to your chosen specialization.
Choosing a Data Science Focus for Your MSIS
Are you interested in the overlap between information systems, analytics, and business decision-making? Some MSIS programs let students combine data-focused coursework with the study of information systems in organizational and business settings. Look for an MSIS program that offers concentrations, specializations, or electives in areas such as data analytics, business intelligence, or analytics and AI. Look for an MSIS program that offers concentrations in data analytics or business intelligence.
Depending on the program, students in these tracks may take courses in topics such as:
- Database or data warehouse design
- Quantitative and statistical analysis
- Data mining or predictive analytics
- Data visualization and presentation
Other Related Online Degree Programs
If you’re interested in master’s degrees outside of information science, explore online programs in related areas:
FAQs
A Master of Science in Information Systems (MSIS) may help you qualify for or advance in roles related to business technology, systems analysis, data management, cybersecurity, or IT management, depending on your background and the program’s focus. Depending on your experience, an MSIS may be useful for roles such as database administrator, database architect, systems analyst, or computer and information systems manager. For leadership titles such as chief technology officer, employers often expect substantial prior experience in addition to graduate education.
Master's in Information Systems Programs
Browse updated listings for Master of Science in Information Systems (MSIS) programs below.
If you represent a university and would like to contact us about a listing, please email info@mastersindatascience.org. The university’s website is the best place to find the most up-to-date information on programs and offerings.
Browse schools by state
Alabama | Arizona | Arkansas | California | Colorado | District of Columbia | Florida | Georgia | Illinois | Indiana | International | Iowa | Maine | Maryland | Massachusetts | Mississippi | Missouri | Nevada | New Hampshire | New Jersey | New York | North Dakota | Oklahoma | Pennsylvania | South Dakota | Tennessee | Texas | Utah | Virginia | Washington
Alabama
Arkansas
Colorado
Indiana
International
Iowa
Maine
Maryland
Massachusetts
Mississippi
Missouri
Nevada
New Hampshire
New Jersey
North Dakota
Oklahoma
South Dakota
Tennessee
Texas
Washington
Information last updated: April 2026





